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Sens. Joe Manchin and Kyrsten Sinema are the two holdouts as Democrats and the White House try to reach a deal on a sweeping spending bill. But their policy demands may put them at odds.

For a quarter century, Gov't Mule has been rocking hard, led by ex-Allman Brothers guitarist Warren Haynes. Their new release is their first-ever blues album, "Heavy Load Blues."

In 1970, Stephen Sondheim's comic musical Company broke most of the conventions of American musical theater. Now, a newly restored documentary goes inside the making of the original cast album.

NPR's annual list of the year's best albums is full of work by musicians who hit career peaks, discovered their voices or willed something new into reality.

Researchers in South Africa have found that people infected with omicron, on average, are less likely to end up in the hospital. But the variant may act differently here in the U.S.

Your college kid just got home and may be a bit jaded about COVID. But your coming holiday visit could be a real risk to grandparents. Here's how one mom is getting through to her sons about safety.

NPR's Ari Shapiro talks with actress Maggie Gyllenhaal about her directorial debut The Lost Daughter, which takes a unique look at motherhood. Now in theaters, the film will be on Netflix on Dec. 31.

Many public health experts are pushing for stronger measures than the Biden administration and governors are willing to take to reduce impacts from the growing omicron wave. Why the disconnect?

School leaders say the pressures of the pandemic had already made this school year the most challenging of their lives. Then came the omicron variant.

GE announced it's breaking into three. Meanwhile, tech companies continue to take over a wider swath of industries.