The South Carolina Department of Public Health reported a second measles case in Saluda County Monday. The new case is unrelated to the state's measles outbreak that ended April 26 and developed into the nation's largest outbreak since the disease was declared eliminated in 2000.
DPH reported the first international-travel-related case on April 17 in a Saluda County adult who is now out of quarantine. The second person — whose vaccination history is unknown — has been in quarantine and has not caused additional public exposure.
Thirty-nine people will stay in quarantine through May 9.
DPH Deputy Director and Chief Medical Officer Dr. Brannon Traxler said in a statement that the agency's strategies to prevent further case spread from the exposure have been successful.
"All measures to limit this initial exposure and prevent further cases have been successful so far," Traxler said. "This second case was from an exposure identified when we first learned of the initial case in Saluda County last month, and this individual had been quarantining to see if symptoms would develop. Because the individual was already quarantining, no one else was exposed when symptoms developed."
The agency said vaccination continues to be the best way to prevent measles. Of cases with a known vaccination status in the state's recent outbreak, 94% were in fully unvaccinated people.
The total number of cases in the state since July 2025 is now 1,002; just five of the state's measles cases since July 2025 are not part of the now-ended outbreak total.
